功能基因筛选方法的研究进展
网站地图本站论坛
高级搜索收藏本站
 
 当前位置:试验方案>核酸试验>DNA试验>基础知识> 正文

功能基因筛选方法的研究进展

点击:   作者:   来源:  时间: 1970-01-01  本站论坛

[19 ]  Zhao Z, Cao Y, Li M, et al . Double2stranded RNA injection produces non2specific defects in zebrafish [ J ] . Dev Biol , 2001 , 229(1) :215 - 223.
[20 ]  Elbashir SM, Harborth J , Lendeckel W, et al . Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells [J ] . Nature , 2001 , 411 (6836) :494 -498.
[21 ]  Brummelkamp TR , Bernards R , Agami R. A system for stable expression of short interfering RNAs in mammalian cells[J ] . Science , 2002 , 296(5567) :550 - 553.
[22 ]  Paul CP , Good PD , Winer I , et al . Effective expression of small interfering RNA in human cells[J ] . Nat Biotechnol , 2002 , 20(5) :505 - 508.
[23 ]  Kimber WL , Puri N , Borgmeyer C , et al . Efficacy of 2-methoxyethoxy2modified antisense oligonucleotides for the study of mouse preimplantation development [ J ] . Reprod Biomed Online , 2003 , 6(3) :318 - 322.
[24 ]  Faneca H , Simoes S , de Lima MC. Evaluation of lipid-based reagents to mediate intracellular gene delivery [ J ] .Biochim Biophys Acta , 2002 , 1567(1/ 2) :23 - 33.
[25 ]  Huang ZY, Wu Y, Burke SP , et al . The 43 000 growth-associated protein functions as a negative growth regulator in glioma[J ] . Cancer Res , 2003 , 63(11) :2933 - 2939.
[26 ]  Walke DW, Han C , ShawJ , et al . In vivo drug target discovery: identifying the best targets from the genome [ J ] .Curr Opin Biotechnol , 2001 , 12(6) :626 - 631.
[27 ]  Tornell J , Snaith M. Transgenic systems in drug discovery :from target identification to humanized mice [J ] . Drug Discov Today , 2002 , 7(8) :461 - 470.
[28 ]  Bailey SN , Wu RZ, Sabatini DM. Applications of transfected cell microarrays in high2throughput drug discovery [J ] .Drug Discov Today , 2002 , 7(18 Suppl) :S113 - S118.
[29 ]  Biran I , Walt DR. Optical imaging fiber-based single live cell arrays : a high-density cell assay platform[ J ] . Anal Chem , 2002 , 74(13) :3046 - 3054.
[30 ]  Kamme F , Salunga R , Yu J , et al . Single2cell microarray analysis in hippocampus CA1 : demonstration and validation of cellular heterogeneity [J ] . J Neurosci , 2003 , 23 (9) :3607 - 3615.


上一篇:基因打靶技术   下一篇:DNA 计算分析(DNA Computational Analysis)


共5页: 上一页 [1] [2] [3] [4] 5 下一页

 
推荐文章
 
相关文章
推荐专题


↑返回顶部   打印本页   关闭窗口↓  
 本站申明 联系我们 网站地图
Copyright© 试验方案

Powered by DedeCms email:htmyth#yahoo.com.cn

Optimized to 1024x768 to Firefox,Opera and MS-IE6