2006年10月19日 Nature中英文摘要
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2006年10月19日 Nature中英文摘要

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Volume 443 Number 7113 pp723-882   (19 October 2006)

October 19, 2006
封面故事:美中期选举在科学问题上做文章

11月的中期选举关系重大:民主党在众议院中只需要15个席位、在参议院中只需要6个席位就能成为多数党。对布什总统来说,这可能意味着一个重振雄风的总统任期或一个无所作为的“跛鸭”期之间的区别。在一个差距很小的选举中,两党都在偶然地、非典型地转向科学来试图影响选民。总统最近通过行使否决权来否决胚胎干细胞研究的做法,为共和党和民主党试图证明各自的候选人与众不同的努力都提供了新的素材。在三个州,候选人主要依据科学问题(气候变化和干细胞研究)挑战现任议员;而在加州,候选人将不可避免地要在清洁能源问题上做文章。本期的一篇News Feature特稿分析了科学问题是怎样被利用到选举活动中的。


October 19, 2006
地壳的形成速度

地球的大陆壳在该星球演化中扮演一个关键角色,然而大陆壳是什么时候和怎样形成的却仍然是一个很有争议的问题。对新生成的大陆壳中的同位素含量进行分析方面的进展,近年来使科学家能够建立关于壳层演化的更可靠的模型。Chris Hawkesworth 和 Tony Kemp对这这些进展进行了综述。将地壳分异模型与元素在上层地壳中的驻留时间结合起来,研究人员发现,地壳形成的平均速度比以前的大多数估计数字高二到三倍。


October 19, 2006
真菌的共同祖先

AFTOL项目(即“组装真菌的生命树”项目)是为了将植物分类记录理顺而设立的一个研究项目。真菌是生物分类中的主要的“界”之一,这主要是因为它们的尺寸较小和它们的化石记录较差。现在,参加AFTOL项目的真菌学家通过跟踪近200个物种的6个基因区域重建了真菌的早期演化。所有真菌最后的共同祖先都被重建为一种带鞭毛的、有点像变形虫的、很可能过着寄生生活的生物,很像Rozella allomycis,后者是水生真菌和藻类中的一种寄生虫。


October 19, 2006
一种新的脱落酸受体

脱落酸(Abscisic acid)是一种至关重要的植物激素,主要调控气孔和种子发育。最近的一篇Nature论文识别出,结合RNA的蛋白FCA是一种脱落酸受体,参与对开花和根的形成的控制。而控制植物种子发育、气孔和对干旱适应性的受体仍然没有找到。现在,有了一个意想不到的消息:一种参与叶绿素生物合成的分子,即镁螯合酶的H-亚单元(H-subunit of Mg-chelatase)也是一种脱落酸受体。这种相互作用控制种子发芽和气孔运动,所以它与那个“所缺的”受体的特征相符。


October 19, 2006
M31星系的一个由尘埃构成的内环

“仙女座”星系(Messier 31)在星系演化研究中是一个大星系,因为它是距我们最近的巨型螺旋形星系,是所谓的“本地星系群”中最大的之一。它看起来很奇特,其外观长期以来使天文学家感到困惑。它有一个著名的、偏离星系核心的外环,该外环是弯曲的。现在,科学家在“斯皮策天文望远镜”的近红外图像中发现了一个由尘埃构成的内环。这个环偏离星系的中心。数值模拟表明,两个环都是由一个相伴的星系形成的,后者几乎迎头穿过M31星系的环的中心。最有可能的“入侵者”是矮星系M32。


October 19, 2006
月球南极陨石坑没有发现存在厚冰的证据

月球南极“沙克尔顿”陨石坑边缘是美国国家航空航天局(NASA)的LCROSS探测器(LCROSS是“月球陨石坑观测和传感卫星”的缩写)的一个候选着陆点,该探测器定于2008年发射。研究人员将对着陆时激起的尘埃进行分析,希望能够找到水的证据,那里被认为是有水的。认为月球上有冰的观点是在1996年提出的,当时来自“克莱门汀”宇宙飞船的数据表明,月球南极陨石坑壁上有冰。现在,利用高分辨率雷达图像,研究人员发现,被认为表示存在厚的冰层的雷达散射参数,也符合布满岩石的陨石坑壁及在月球所有纬度上的年轻碰撞坑的喷出物所产生的雷达回声。 没有发现存在厚冰的证据,虽然月球土壤中可能散布着较薄的水冰颗粒。


October 19, 2006
能够克服“量子去相干”障碍的方法

实用量子计算和量子通信的一个障碍是“量子去相干”。现在,研究人员已经找到了一种可以帮助解决这一问题的手段。它是两个物理上分开的量子系统之间的纠缠态,该纠缠态使得量子通信和信息处理成为可能;“去相干”是在纠缠态被分布时出现的,使得系统的量子性质能够泄露到周围环境中,并降低所发送的纠缠对的质量。新的纠缠净化协议通过以一种高效的、非破坏性的方式将高保真纠缠对从低保真纠缠对中提取出来,从而克服了这一问题。



October 19, 2006
一种新型合成沸石

沸石是在电子、催化、气体存储和其他领域有很多用途的多孔材料。现在,一种新的名叫ITQ-33的沸石已被合成出来,它较以前的有非常大的微孔容积的化合物有优势。正如理论工作者在1989年所预测的,要获得这样大的一个“笼状”尺寸,该结构应当有大量的、由四个成员和三个成员组成的环。除了有很大的微孔容积外(例如可以有很大的气体存储容量),由中等大小的孔所连接的大孔的存在,应当使该材料具有极为有用的催化性能。



October 19, 2006
海洋触发了气候突变

关于上个冰期-间冰期过渡阶段千年尺度的气候变化的一个关键问题是,是否是海洋或者大气触发了突然的气候变化。具体来说,海洋的热盐循环的重组或者与今天的“厄尔尼诺-南方涛动”事件类似的热带大气-海洋动态可能与突然的气候变化有关。对过去3万年赤道太平洋中海洋表面温度所做的一个高分辨率重建表明,海洋为气候变化的触发因素,至少在被称为“Heinrich event 1”和“Younger Dryas”的事件期间是这样。



October 19, 2006
海底泥浆火山是甲烷主要排放源的原因

海底泥浆火山可能是温室气体甲烷的主要排放来源。其中的一些气体被名叫“嗜甲烷菌”(methanotroph)的微生物消耗掉了,但相对来说很少有微生物能利用甲烷,而且相关的过程也不是很清楚。对巴伦支海中一个泥浆火山周围的水域所做的一项研究工作,识别出三个关键的“嗜甲烷菌”群略:需氧细菌、生活在管虫之下的厌氧古细菌、以及以前未被描述过的与细菌垫相关的古细菌。研究人员还发现了微生物甲烷过滤容量的一个自然高限:不含硫酸盐和氧气的火山流体的向上流动限制了甲烷氧化的效率,使大部分甲烷能够逃逸到水圈,并有可能逃逸到大气中。


October 19, 2006
捕捞对海洋渔业资源的影响

捕捞会通过将鱼类从海洋中除掉而消耗鱼类资源存量,这是很显然的事情。但在上个世纪70年代后期,理论工作者曾提出,捕捞也许还能降低某种鱼类种群在面对变化时的恢复能力。关于这个问题的讨论此前一直是理论上的。现在,对50年来加州海域鱼苗存量所做的一项调查(该调查开始于上个世纪40年代沙丁鱼种群崩溃之后),为我们提供了所缺的数据。似乎捕捞的确能够增大种群的可变性(降低恢复能力),其作用方式超过了将鱼类从海洋中拿走这个事实本身。由于较大的鱼和较老的鱼首先被捕捞而造成的年龄结构的中断很可能是原因之所在。这说明,要避免种群崩溃,渔业管理必须不仅要维持总生物量,而且要维持种群的年龄结构。



October 19, 2006
用语言学模型分析研究抗菌肽

抗菌肽是由多细胞真核生物的先天免疫系统产生的,它们可能不像其他抗生素那样易受细菌抗药性的影响。一个语言学模型被用来分析自然出现的抗菌肽,所获得的信息又被用来设计一系列新的抗菌肽,它们与天然出现的肽几乎没有同源关系,但对几种细菌却有抗菌活性,包括金葡萄球菌(Staphylococcus aureus)和炭疽杆菌(Bacillus anthracis)。




Contents

Editorials
AIDS and the private sector p723
It will take more than awareness to slow the HIV pandemic in Africa.

doi:10.1038/443723a

Full Text | PDF (103K)

See also: Editor's summary


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Striving for excellence p723
A German exercise to foster élite universities began inauspiciously but is a step in the right direction.

doi:10.1038/443723b

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A state of flux p724
A fresh start beckons for the politics of US science.

doi:10.1038/443724a

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Top of pageResearch Highlights
Research highlights p726
doi:10.1038/443726a

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Top of pageNews
Iraqi death toll withstands scrutiny p728
Conflict epidemiology study counts the cost of war.

Jim Giles

doi:10.1038/443728a

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Snapshot: Light show p729
Cassini captures the dark side of Saturn.

Nicola Jones

doi:10.1038/443729a

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Is ice on the Moon just a mirage? p730
Radar images dash hopes for Moonbase water supply.

Katharine Sanderson

doi:10.1038/443730a

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Missing results might have rung warning bell over trial drug p730
Drug-safety experts call for more rigorous risk assessments.

Helen Pearson

doi:10.1038/443730b

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Kudos, not cash, is the real X-factor p733
X Prize targets rapid-fire sequencing of individual genomes.

Heidi Ledford

doi:10.1038/443733a

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Sidelines p734
doi:10.1038/443734a

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Japan's new premier chases innovation p734
Prime minister breaks with tradition to appoint scientist as special adviser.

Ichiko Fuyuno

doi:10.1038/443734b

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News in brief p736
doi:10.1038/443736a

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Correction p737
doi:10.1038/443737a

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Top of pageBusiness
A firm response to AIDS p738
'Product Red' is the private sector's bid to fight HIV. But is it too little too late? Colin Macilwain investigates.

doi:10.1038/443738a

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In brief p739
doi:10.1038/443739a

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Market watch p739
Colin Macilwain

doi:10.1038/443739b

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Top of pageNews Features
US election: Showdown for Capitol Hill p740
Can science influence politics in the forthcoming US elections? Nature investigates how Democrats and Republicans are striving to win the hearts of voters.

doi:10.1038/443740a

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See also: Editor's summary


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Q&A p744
Representative Rush Holt is a rare thing in the US Congress — a bona fide scientist building a promising political career. Since his election for the 12th district of New Jersey — the one containing Princeton — eight years ago, this former physicist and son of a West Virginia senator has garnered several powerful committee slots. Holt has emerged as one of the Democratic Party's most prominent spokesmen on science, education and security. Colin Macilwain asked him about the life of a scientist on Capitol Hill, and what the mid-term elections could mean for science and education.

doi:10.1038/443744a

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A life online p746
Darwin is the latest eminent scientist to get an online archive. How do these undertakings change our understanding of history, asks Henry Nicholls.

doi:10.1038/443746a

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See also: Editor's summary


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Top of pageCorrespondence
Nature: the many benefits of ecosystem services p749
Walter V. Reid

doi:10.1038/443749a

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Nature: ecosystems without commodifying them p749
Robert Costanza

doi:10.1038/443749b

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Nature: poorest may see it as their economic rival p749
Michelle Marvier, Joy Grant and Peter Kareiva

doi:10.1038/443749c

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Nature: McCauley replies p750
Douglas J. McCauley

doi:10.1038/443749d

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Melanoma rates remain high in Australia p750
Jonathan Rees

doi:10.1038/443749e

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Getting the public on board for cancer screening p750
Ramesh P. Arasaradnam

doi:10.1038/443749f

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Top of pageCommentary
Planning for US science policy in 2009 p751
To maximize the resources allocated to science and technology during the next US administration the science community must prepare now, argues Thomas Kalil.

doi:10.1038/443751a

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Top of pageBooks and Arts
What just ain't so p753
It is all too easy to underestimate the challenges posed by climate change.

Roger A. Pielke, Jr reviews Kicking the Carbon Habit: Global Warming and the Case for Renewable and Nuclear Energy by William Sweet

doi:10.1038/443753a

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The road to phage therapy p754
Sankar Adhya and Carl Merril review Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? by Thomas Häusler

doi:10.1038/443754a

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Eeyore goes to Washington p755
Peter Parham reviews The Beginner's Guide to Winning the Nobel Prize: A Life in Science by Peter Doherty

doi:10.1038/443755a

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New in paperback p755
doi:10.1038/443755b

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Science in Culture: Pictures from the edge of darkness p756
Eight photographers enter the twilight zone.

Colin Martin

doi:10.1038/443756a

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Top of pageNews and Views
Chemistry: The promise of emptiness p757
Zeolites are materials with widespread applications. A newly synthesized example has desirably large pores, as well as the virtue of thermal stability, and shows the value of structure-prediction programs.

Raul F. Lobo

doi:10.1038/443757a

Full Text | PDF (329K)

See also: Editor's summary


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Evolutionary biology: A kingdom revised p758
An international consortium of researchers has produced an impressive new tree of life for the kingdom Fungi. The results are a testament to cooperation between systematists with different expertise.

Tom Bruns

doi:10.1038/443758a

Full Text | PDF (318K)

See also: Editor's summary


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Structural biology: Enzyme target to latch on to p761
Insulin-degrading enzyme is implicated in diabetes and Alzheimer's disease, but few molecular tools exist that can probe its function. A study now reveals its unusual structure and may lead to an expanded toolbox.

Malcolm A. Leissring and Dennis J. Selkoe

doi:10.1038/nature05210

Full Text | PDF (300K)

See also: Editor's summary


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Astronomy: Andromeda's troubled past p762
Tim Lincoln

doi:10.1038/443762b

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Palaeoanthropology: Return of the last Neanderthal p762
New finds from Gibraltar date Mousterian tools to as recently as 28,000 years ago. By inference, their Neanderthal makers survived in southern Iberia long after all other well-dated occurrences of the species.

Eric Delson and Katerina Harvati

doi:10.1038/nature05207

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Top of pageBrief Communications
Three-dimensional miniature endoscopy p765
A single optical fibre acts as a flexible probe to transmit a superior image of an internal landscape.

D. Yelin, I. Rizvi, W. M. White, J. T. Motz, T. Hasan, B. E. Bouma and G. J. Tearney

doi:10.1038/443765a

Full Text | PDF (212K) | Supplementary information

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Top of pageInsight
Neurodegeneration p767
Marie-Thérèse Heemels

doi:10.1038/443767a

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A network dysfunction perspective on neurodegenerative diseases p768
Jorge J. Palop, Jeannie Chin and Lennart Mucke

doi:10.1038/nature05289

Abstract | Full Text | PDF (468K)


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A century-old debate on protein aggregation and neurodegeneration enters the clinic p774
Peter T. Lansbury and Hilal A. Lashuel

doi:10.1038/nature05290

Abstract | Full Text | PDF (367K)


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The roles of intracellular protein-degradation pathways in neurodegeneration p780
David C. Rubinsztein

doi:10.1038/nature05291

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases p787
Michael T. Lin and M. Flint Beal

doi:10.1038/nature05292

Abstract | Full Text | PDF (581K)


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Cell death in the nervous system p796
Dale E. Bredesen, Rammohan V. Rao and Patrick Mehlen

doi:10.1038/nature05293

Abstract | Full Text | PDF (519K)


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Prions and their partners in crime p803
Byron Caughey and Gerald S. Baron

doi:10.1038/nature05294

Abstract | Full Text | PDF (3,287K)


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Top of pageReview
Evolution of the continental crust p811
C. J. Hawkesworth and A. I. S. Kemp

doi:10.1038/nature05191

Abstract | Full Text | PDF (374K)

See also: Editor's summary


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Top of pageArticles
Reconstructing the early evolution of Fungi using a six-gene phylogeny p818
Timothy Y. James, Frank Kauff, Conrad L. Schoch, P. Brandon Matheny, Valérie Hofstetter, Cymon J. Cox, Gail Celio, Cécile Gueidan, Emily Fraker, Jolanta Miadlikowska, H. Thorsten Lumbsch, Alexandra Rauhut, Valérie Reeb, A. Elizabeth Arnold, Anja Amtoft, Jason E. Stajich, Kentaro Hosaka, Gi-Ho Sung, Desiree Johnson, Ben O'Rourke, Michael Crockett, Manfred Binder, Judd M. Curtis, Jason C. Slot, Zheng Wang, Andrew W. Wilson, Arthur Schüler, Joyce E. Longcore, Kerry O'Donnell, Sharon Mozley-Standridge, David Porter, Peter M. Letcher, Martha J. Powell, John W. Taylor, Merlin M. White, Gareth W. Griffith, David R. Davies, Richard A. Humber, Joseph B. Morton, Junta Sugiyama, Amy Y. Rossman, Jack D. Rogers, Don H. Pfister, David Hewitt, Karen Hansen, Sarah Hambleton, Robert A. Shoemaker, Jan Kohlmeyer, Brigitte Volkmann-Kohlmeyer, Robert A. Spotts, Maryna Serdani, Pedro W. Crous, Karen W. Hughes, Kenji Matsuura, Ewald Langer, Gitta Langer, Wendy A. Untereiner, Robert Lücking, Burkhard Büdel, David M. Geiser, André Aptroot, Paul Diederich, Imke Schmitt, Matthias Schultz, Rebecca Yahr, David S. Hibbett, François Lutzoni, David J. McLaughlin, Joseph W. Spatafora and Rytas Vilgalys

doi:10.1038/nature05110

Abstract | Full Text | PDF (261K) | Supplementary information

See also: Editor's summary


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The Mg-chelatase H subunit is an abscisic acid receptor p823
Yuan-Yue Shen, Xiao-Fang Wang, Fu-Qing Wu, Shu-Yuan Du, Zheng Cao, Yi Shang, Xiu-Ling Wang, Chang-Cao Peng, Xiang-Chun Yu, Sai-Yong Zhu, Ren-Chun Fan, Yan-Hong Xu and Da-Peng Zhang

doi:10.1038/nature05176

Abstract | Full Text | PDF (528K) | Supplementary information

See also: Editor's summary


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Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase p827
Min Deng and Mark Hochstrasser

doi:10.1038/nature05170

Abstract | Full Text | PDF (392K) | Supplementary information


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Top of pageLetters
An almost head-on collision as the origin of two off-centre rings in the Andromeda galaxy p832
D. L. Block, F. Bournaud, F. Combes, R. Groess, P. Barmby, M. L. N. Ashby, G. G. Fazio, M. A. Pahre and S. P. Willner

doi:10.1038/nature05184

First paragraph | Full Text | PDF (385K) | Supplementary information

See also: Editor's summary


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No evidence for thick deposits of ice at the lunar south pole p835
Donald B. Campbell, Bruce A. Campbell, Lynn M. Carter, Jean-Luc Margot and Nicholas J. S. Stacy

doi:10.1038/nature05167

First paragraph | Full Text | PDF (735K)

See also: Editor's summary


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Experimental purification of two-atom entanglement p838
R. Reichle, D. Leibfried, E. Knill, J. Britton, R. B. Blakestad, J. D. Jost, C. Langer, R. Ozeri, S. Seidelin and D. J. Wineland

doi:10.1038/nature05146

First paragraph | Full Text | PDF (216K)

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High-throughput synthesis and catalytic properties of a molecular sieve with 18- and 10-member rings p842
Avelino Corma, María J. Díaz-Cabañas, José Luis Jordá, Cristina Martínez and Manuel Moliner

doi:10.1038/nature05238

First paragraph | Full Text | PDF (377K) | Supplementary information

See also: Editor's summary


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Eastern Pacific cooling and Atlantic overturning circulation during the last deglaciation p846
Markus Kienast, Stephanie S. Kienast, Stephen E. Calvert, Timothy I. Eglinton, Gesine Mollenhauer, Roger François and Alan C. Mix

doi:10.1038/nature05222

First paragraph | Full Text | PDF (345K) | Supplementary information

See also: Editor's summary


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Late survival of Neanderthals at the southernmost extreme of Europe p850
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Novel microbial communities of the Haakon Mosby mud volcano and their role as a methane sink p854
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Fishing elevates variability in the abundance of exploited species p859
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An early evolutionary origin for the minor spliceosome p863
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A linguistic model for the rational design of antimicrobial peptides p867
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Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism p870
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Direct observation of individual RecA filaments assembling on single DNA molecules p875
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Top of pageNaturejobs
Prospect
Prospects p879
EMBO awardees reveal blueprints for success.

Paul Smaglik

doi:10.1038/nj7113-879a

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Career Views
Luis Serrano, director, Systems Biology Research Unit, Barcelona Biomedical Research Park, Barcelona, Spain p880
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doi:10.1038/nj7113-880a

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Training peer reviewers p880
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Computer cold turkey p880
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Highlights
Highlight: Ohio
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Highlight: The National Institutes of Health
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Top of pageFutures
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Immortal remains.

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doi:10.1038/443882a

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