Volume 443 Number 7114 ppxiii-1030 (26 October 2006) October 26, 2006
封面故事：蜜蜂基因组完成测序
“蜜蜂基因组测序联合课题组”本周发表了蜜蜂Apis mellifera的完整基因组序列。蜜蜂通过授粉对全球生态具有重要影响，它们也是研究社会行为的一种关键模型。该基因组所含主管先天免疫、表皮形成和味觉受体的基因数量少于其他昆虫，但所含气味受体多于其他昆虫，并且含有用于花蜜和花粉利用的新颖基因。种群遗传学知识有助于我们了解非洲化蜜蜂是否是通过杂交或迁移从“新世界”向外扩散的。在配发的一篇News and Views文章中，E. O. Wilson对“将蜜蜂提升到一个高级的社会组织状态”的深远的生物学变化是怎样反映在新测序的基因组中的进行了分析。封面所示为一株犬齿赤莲上的一只蜜蜂。（Carrol W. Perkins/photolibrary.com）
October 26, 2006
一种当“甩手掌柜”的蠕虫
Olavius algarvensis是一种海洋寡毛纲蠕虫，存在于地中海厄尔巴岛沿海浅水沙子中。它们的解剖特征是引人注目的，因为它们不但没有嘴、胃和肠，而且没有肾管（nephridia），即肾脏一样的器官。消化系统的省略出现在其他动物中，但这种动物是惟一省略了自己的排泄系统以适应共生方式的寄主。现在，生活在这些蠕虫皮肤下面的共生细菌群落的基因组成已被确定。多源基因组分析揭示了如此多的重要寄主任务何以被外包给了共生体。
October 26, 2006
燧石能够反映海水温度变化的史
燧石是含有石英微晶的致密的硅质岩石，是地球上保存最完好的海洋沉积物之一，其形成涵盖的时间段从距今35亿年前的太古代早期到现在。新的数据表明，燧石的硅同位素组成随地质年龄有系统性变化，并且与氧同位素组成具有相关性。这意味着，燧石的同位素组成很可能记录了它们的形成温度。利用关于硅循环数值模型从这些数据获得的同位素曲线，提供了前寒武纪海水温度变化的一个独特记录，其变化从距今35亿年前到距今8亿年前在70摄氏度至20摄氏度之间。
October 26, 2006
水合作用对地幔物质电导性的影响
地幔的性质（如粘度和熔化温度）受含水量严重影响。然而，确定地幔含水量仍然富有挑战性。曾有人提出，橄榄石的水合作用是岩流圈（地壳和上层地幔下面的可变形层）高电导性的原因，但水对这些物质的影响（通过氢的结合而产生）尚未在实验室中确定。现在，两个小组报告了关于氢对橄榄石电导性影响的实验结果。他们都发现，少量氢能急剧增加电导性，但它们关于这种水合作用是否能够解释所观察到的地幔电导性的结论却不一致。显然，需要进行更多工作来确定这种偏差背后的因素。
October 26, 2006
南非发现迄今最古老七鳃鳗化石
七鳃鳗和八目鳗是现存惟一无颚脊椎动物，在关于现存有颚脊椎动物的比较研究中普遍被用作“代理祖先”。直到不久前，科学家对七鳃鳗的演化历史还知之甚少，因为惟一已知化石是来自距今约3亿年前的石炭纪时期的谜一样的样本。后来，今年早些时候，Nature发表了来自中国石炭纪地层的一个精细化石标本，它看起来非常接近现代形式。现在，又有了一个来自南非泥盆纪地层的保存完好的化石，距今约3.6亿年，是已知最古老的七鳃鳗。它看起来与现代七鳃鳗稍有不同，但在重要方面都是一样的，而与同样来自泥盆纪的各种不同的、现已灭绝的披甲鱼类有所不同。
October 26, 2006
决定四肢形状的遗传因素
四足动物四肢前后极性，即可解释为什么你的大拇指和小拇指是不同的等现象的不对称性， 是由Sonic hedgehog (Shh)基因在胚胎肢芽（limb bud）后部的表达早就确定了的。Shh表达反过来由HoxA 和 HoxD类群中的基因控制的。Tarchini等人发现，Shh基因由Hox类群中更靠后的成员控制，也就是说，由那些其表达因它们的同线性转录激发而被排除在最靠前肢芽之外的基因控制。换句话说，四肢形状的形成，是躯干中Hox基因表达的同线性的一个副作用，这便为关于演化过程用可供利用的原材料来做什么的理论施加了一个遗传学上的约束条件。
October 26, 2006
物种损失对生态系统功能的影响
关于物种灭绝是否会改变群落生产力和生态系统功能的问题，是一个争议非常大的问题。上个世纪90年代所做的研究工作表明，物种损失可降低群落的生产力，降低它们捕捉和消耗有限资源方面的效率。对这些研究结果的理解是有争议的，后来的研究工作产生了若干反例，这些反例使关于生物多样性效应的普遍性受到质疑。现在，Cardinale等人报告了对关于物种多样性和生态功能的实验研究所进行的一次“多源分析”（meta-analysis）结果。他们的结论是，物种损失的确影响生态功能，但影响的程度取决于具体损失的是哪些物种。
October 26, 2006
角膜中的抗血管生成分子
角膜是身体上少数没有血管在其中流通的组织之一。这个没有血管的“岛屿”经常被用来试验癌症、关节炎、动脉硬化、糖尿病和由病理性血管生成驱动的其他疾病的抗血管生成疗法。该组织没有血管是引人注目的，这是由于其周围组织都有高度发达的血管，而更为引人注目的是因为角膜现在被发现含有大量强效抗血管生成分子VEGF-A (血管内皮生长因子)。该发现又导致了一个对药物设计而很重要的发现：作为一种可溶性VEGFR-1的一种VEGF-A 阱也存在于角膜中，角膜中没有血管正是由该物质这一个因素造成的。有趣的是，已知含血管角膜的少数动物（海牛、突变小鼠和一些有Pax6突变的先天性无虹膜症患者）都缺少角膜可溶性VEGFR-1。
October 26, 2006
可用于风湿性关节炎药物研究的动物模型
用于治疗风湿性关节炎的药物的开发 一直没有一种好的动物模型的帮助。现在，一种新开发的突变小鼠模型有可能帮助填补这个空白。这种小鼠缺少DNaseII基因，是被第二个突变从那个突变的致命影响中拯救过来的，这第二个突变允许干扰素的组成性生成。这种小鼠患了慢性多发性关节炎，与人类的风湿性关节炎类似，原因是在细胞程序死亡和定向红血球生成过程中DNA降解失败了。这是出乎意料的：对各种不同小鼠组织所做的分析表明，携带未降解DNA的巨噬细胞会被激活，产生TNF（肿瘤坏死因子），导致多发性关节炎的发展。有趣的是，TNF与风湿性关节炎的发病有关，抗TNF疗法有时被用来治疗该疾病。
October 26, 2006
基因放大的新机制
基因放大的一种以前不知道的机制，已在酿酒酵母(Saccharomyces cerevisiae)中被发现，它涉及基因组中包含组蛋白基因、一个端粒和DNA复制起源的一个区域两侧的转位子之间的重组。转位子序列物理上交联、重组为一个稳定的环形染色体，含有被放大的基因。这一特定的重组事件在组蛋白H2A 和 H2B水平下降的细胞中得到加强。类似机制人类可能也有，因为人类基因组45%由转位子组成。
ContentsAuthors
Making the paper: Tanja Woyke pxiii
Genomes, in microbes, in worms, in mud, in the Mediterranean.
doi:10.1038/7114xiiia
Full Text | PDF (124K)
--------------------------------------------------------------------------------
Abstractions: Project Leader pxiii
doi:10.1038/7114xiiib
Full Text | PDF (124K)
--------------------------------------------------------------------------------
Key Collaborator pxiii
doi:10.1038/7114xiiic
Full Text | PDF (124K)
--------------------------------------------------------------------------------
Top of pageEditorials
Europe's arrested development p883
Encouraging statistics on industrial R&D don't tell the whole story.
doi:10.1038/443883a
Full Text | PDF (99K)
--------------------------------------------------------------------------------
Rich in plutonium p883
The US nuclear-weapons complex is too large — and is likely to remain so.
doi:10.1038/443883b
Full Text | PDF (127K)
--------------------------------------------------------------------------------
Plan bee p884
Another day, another genome.
doi:10.1038/443884a
Full Text | PDF (89K)
See also: Editor's summary
--------------------------------------------------------------------------------
Top of pageResearch Highlights
Research highlights p886
doi:10.1038/443886a
Full Text | PDF (370K)
--------------------------------------------------------------------------------
Top of pageNews
'A shocking lack of evidence' p888
The trial in Libya of six medics accused of infecting children with HIV ends next week. With the defendants facing possible execution, Declan Butler asked AIDS experts to assess the case against them.
doi:10.1038/443888a
Full Text | PDF (374K)
--------------------------------------------------------------------------------
Sidelines p890
doi:10.1038/443890a
Full Text | PDF (140K)
--------------------------------------------------------------------------------
Sceptics detect flaws in US nuclear monitor plan p890
Can North Korea's nuclear advances be contained?
Geoff Brumfiel
doi:10.1038/443890b
Full Text | PDF (306K)
--------------------------------------------------------------------------------
Polish scientists fight creationism p890
Deputy education minister calls evolution a 'lie'.
Almut Graebsch
doi:10.1038/443890c
Full Text | PDF (306K)
--------------------------------------------------------------------------------
From hive minds to humans p893
Honeybee genome offers insight into social behaviour.
Erika Check
doi:10.1038/443893a
Full Text | PDF (236K)
See also: Editor's summary
--------------------------------------------------------------------------------
Grants fall victim to NIH success p894
Increase in applications sees funding rate plummet.
Jim Giles and Meredith Wadman
doi:10.1038/443894a
Full Text | PDF (550K)
--------------------------------------------------------------------------------
Funding agencies toughen stance on open access p894
Pressure grows for scientists to make research free for all.
Heidi Ledford
doi:10.1038/443894b
Full Text | PDF (550K)
--------------------------------------------------------------------------------
Snapshot: But is it natural? p895
Doors open on exhibition of animal homosexuality.
Alison Abbott
doi:10.1038/443895a
Full Text | PDF (503K)
--------------------------------------------------------------------------------
News in brief p896
doi:10.1038/443896a
Full Text | PDF (213K)
--------------------------------------------------------------------------------
Top of pageBusiness
Capital gains p897
London is seeking to compete with the Nasdaq as the preferred global venue for science-based companies trying to raise cash. Andrea Chipman reports.
doi:10.1038/443897a
Full Text | PDF (225K)
--------------------------------------------------------------------------------
Top of pageNews Features
Whitefly infestations: The Christmas Invasion p898
The cheerful leaves of the poinsettia could be hiding an unwelcome visitor this festive season. Rex Dalton goes in search of the whitefly, a potentially devastating pest.
doi:10.1038/443898a
Full Text | PDF (1,044K)
--------------------------------------------------------------------------------
Cell biology: Power games p901
There's a fight going on inside all our cells for each breath of air. Nick Lane sheds therapeutic light on the implications for cancer and degenerative diseases.
doi:10.1038/443901a
Full Text | PDF (451K)
--------------------------------------------------------------------------------
Marine natural products: Drugs from the deep p904
Is the cure for cancer lurking beneath the waves? Emma Marris plunges into the chemistry of marine natural products.
doi:10.1038/443904a
Full Text | PDF (738K)
--------------------------------------------------------------------------------
Top of pageCorrespondence
RNAi Nobel ignores vital groundwork on plants p906
Marc Bots, Spencer Maughan and Jeroen Nieuwland
doi:10.1038/443906a
Full Text | PDF (93K)
--------------------------------------------------------------------------------
Iran seeks nuclear power to replace reliance on oil p906
Kamran B. Lankarani
doi:10.1038/443906b
Full Text | PDF (93K)
--------------------------------------------------------------------------------
Iran: productivity is not simple to evaluate p906
Hamid Reza Maei
doi:10.1038/443906c
Full Text | PDF (93K)
--------------------------------------------------------------------------------
Iran: let's keep politics in the realm of rationality p906
Ludovico Cademartiri
doi:10.1038/443906d
Full Text | PDF (93K)
--------------------------------------------------------------------------------
Top of pageCommentary
Preparing for the worst p907
An international data bank of nuclear explosives is needed to determine the source of nuclear materials following an explosion, argue Michael May, Jay Davis and Raymond Jeanloz.
doi:10.1038/443907a
Full Text | PDF (326K)
See also: Editor's summary
--------------------------------------------------------------------------------
Top of pageAutumn Books
The Chomsky of morality? p909
A view of morality as the product of an innate mental faculty — rather like language.
Paul Bloom and Izzat Jarudi review Moral Minds: How Nature Designed Our Universal Sense of Right and Wrong by Marc D. Hauser
doi:10.1038/443909a
Full Text | PDF (343K)
See also: Editor's summary
--------------------------------------------------------------------------------
Evidence for evolution p910
Brian Charlesworth reviews The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution by Sean B. Carroll
doi:10.1038/443910a
Full Text | PDF (236K)
See also: Editor's summary
--------------------------------------------------------------------------------
Battlefield between the ears p911
Charles Jennings reviews Mind Wars: Brain Research and National Defense by Jonathan D. Moreno
doi:10.1038/443911a
Full Text | PDF (187K)
See also: Editor's summary
--------------------------------------------------------------------------------
Experimental theatre p913
Stuart Firestein reviews Science on Stage: From Doctor Faustus to Copenhagen by Kirsten Shepherd-Barr
doi:10.1038/443913a
Full Text | PDF (351K)
See also: Editor's summary
--------------------------------------------------------------------------------
Sermons and straw men p914
Lawrence M. Krauss reviews The God Delusion by Richard Dawkins
doi:10.1038/443914a
Full Text | PDF (270K)
See also: Editor's summary
--------------------------------------------------------------------------------
The hero of Gombe p915
W. C. McGrew reviews Jane Goodall: The Woman Who Redefined Man by Dale Peterson
doi:10.1038/443915a
Full Text | PDF (170K)
See also: Editor's summary
--------------------------------------------------------------------------------
The theorist p917
Horace Freeland Judson reviews Francis Crick: Discoverer of the Genetic Code by Matt Ridley
doi:10.1038/443917a
Full Text | PDF (538K)
See also: Editor's summary
--------------------------------------------------------------------------------
Coping with uncertainty p918
Gianpietro Malescio reviews From Cosmos to Chaos: The Science of Unpredictability by Peter Coles
doi:10.1038/443918a
Full Text | PDF (237K)
See also: Editor's summary
--------------------------------------------------------------------------------
Top of pageNews and Views
Genomics: How to make a social insect p919
The profound biological changes that lofted the honeybee to an advanced state of social organization are reflected in its newly sequenced genome. The species can now be studied all the way from molecule to colony.
Edward O. Wilson
doi:10.1038/443919a
Full Text | PDF (349K)
See also: Editor's summary
--------------------------------------------------------------------------------
Palaeoceanography: In hot water p920
There has long been scepticism about the geochemical evidence that the ancient ocean was markedly warm. A fresh approach bolsters the case for an ocean that, in the distant past, was indeed quite hot.
Christina L. De La Rocha
doi:10.1038/443920a
Full Text | PDF (280K)
See also: Editor's summary
--------------------------------------------------------------------------------
Palaeontology: Modern look for ancient lamprey p921
It was once thought that lampreys evolved from armoured jawless vertebrates. But a recently discovered lamprey fossil dates from the twilight age of their supposed ancestors, and looks surprisingly modern.
Philippe Janvier
doi:10.1038/443921a
Full Text | PDF (417K)
See also: Editor's summary
--------------------------------------------------------------------------------
50 & 100 years ago p923
doi:10.1038/443923a
Full Text | PDF (202K)
--------------------------------------------------------------------------------
Electromagnetism: Like a speeding watch p924
A rotation in light's electric-field vector can alter the light's frequency. This rotational equivalent of the Doppler effect has proved surprisingly elusive, but has now been spotted in the laboratory.
Miles Padgett
doi:10.1038/443924a
Full Text | PDF (315K)
--------------------------------------------------------------------------------
Genomics: Blueprints for partnerships p925
Gutless marine worms harness the resources of a team of bacteria in lieu of a digestive or excretory system. A genome-sequence analysis now defines the roles of the microbes.
David A. Stahl and Seana K. Davidson
doi:10.1038/nature05208
Full Text | PDF (288K)
See also: Editor's summary
--------------------------------------------------------------------------------
Geophysics: Protons lead the charge p927
Is the anomalously high electrical conductivity seen in part of Earth's mantle caused by protons derived from hydrous defects in the mineral olivine? Two groups investigate this possibility — and draw different conclusions.
Greg Hirth
doi:10.1038/443927a
Full Text | PDF (164K)
See also: Editor's summary
--------------------------------------------------------------------------------
Developmental biology: Red-eye redirected p928
Barbara Marte
doi:10.1038/443928a
Full Text | PDF (140K)
See also: Editor's summary
--------------------------------------------------------------------------------
Correction p928
doi:10.1038/443928b
Full Text | PDF (140K)
--------------------------------------------------------------------------------
Top of pageBrief Communications
Palaeontology: Skull morphology of giant terror birds p929
These monstrous birds were probably more agile and less portly than previously thought.
Luis M. Chiappe and Sara Bertelli
doi:10.1038/443929a
Full Text | PDF (288K)
See also: Editor's summary
--------------------------------------------------------------------------------
Top of pageBrief Communications Arising
Evolutionary biology: Sympatric plant speciation in islands? pE12
Tod F. Stuessy
doi:10.1038/nature05216
First paragraph | Full Text | PDF (82K)
--------------------------------------------------------------------------------
Evolutionary biology: Sympatric plant speciation in islands? (Reply) pE12
Vincent Savolainen, Christian Lexer, Marie-Charlotte Anstett, Ian Hutton, J. J. Clarkson, M. V. Norup, M. P. Powell, D. Springate, N. Salamin and William J. Baker
doi:10.1038/nature05217
First paragraph | Full Text | PDF (86K)
--------------------------------------------------------------------------------
Top of pageArticles
Insights into social insects from the genome of the honeybee Apis mellifera p931
The Honeybee Genome Sequencing Consortium
doi:10.1038/nature05260
Abstract | Full Text | PDF (4,656K) | Supplementary information
See also: Editor's summary
--------------------------------------------------------------------------------
Symbiosis insights through metagenomic analysis of a microbial consortium p950
Tanja Woyke, Hanno Teeling, Natalia N. Ivanova, Marcel Huntemann, Michael Richter, Frank Oliver Gloeckner, Dario Boffelli, Iain J. Anderson, Kerrie W. Barry, Harris J. Shapiro, Ernest Szeto, Nikos C. Kyrpides, Marc Mussmann, Rudolf Amann, Claudia Bergin, Caroline Ruehland, Edward M. Rubin and Nicole Dubilier
doi:10.1038/nature05192
Abstract | Full Text | PDF (602K) | Supplementary information
See also: News and Views by Stahl & Davidson
--------------------------------------------------------------------------------
Complete crystallographic analysis of the dynamics of CCA sequence addition p956
Kozo Tomita, Ryuichiro Ishitani, Shuya Fukai and Osamu Nureki
doi:10.1038/nature05204
Abstract | Full Text | PDF (843K) | Supplementary information
--------------------------------------------------------------------------------
Top of pageLetters
Evidence for superfluidity of ultracold fermions in an optical lattice p961
J. K. Chin, D. E. Miller, Y. Liu, C. Stan, W. Setiawan, C. Sanner, K. Xu and W. Ketterle
doi:10.1038/nature05224
First paragraph | Full Text | PDF (387K)
--------------------------------------------------------------------------------
Exploration of molecular dynamics during transient sorption of fluids in mesoporous materials p965
Rustem Valiullin, Sergej Naumov, Petrik Galvosas, Jörg Kärger, Hyung-June Woo, Fabien Porcheron and Peter A. Monson
doi:10.1038/nature05183
First paragraph | Full Text | PDF (308K)
--------------------------------------------------------------------------------
A palaeotemperature curve for the Precambrian oceans based on silicon isotopes in cherts p969
François Robert and Marc Chaussidon
doi:10.1038/nature05239
First paragraph | Full Text | PDF (290K) | Supplementary information
See also: Editor's summary | News and Views by De La Rocha
--------------------------------------------------------------------------------
Hydrous olivine unable to account for conductivity anomaly at the top of the asthenosphere p973
Takashi Yoshino, Takuya Matsuzaki, Shigeru Yamashita and Tomoo Katsura
doi:10.1038/nature05223
First paragraph | Full Text | PDF (212K) | Supplementary information
See also: Editor's summary | News and Views by Hirth
--------------------------------------------------------------------------------
The effect of water on the electrical conductivity of olivine p977
Duojun Wang, Mainak Mookherjee, Yousheng Xu and Shun-ichiro Karato
doi:10.1038/nature05256
First paragraph | Full Text | PDF (239K) | Supplementary information
See also: Editor's summary | News and Views by Hirth
--------------------------------------------------------------------------------
A lamprey from the Devonian period of South Africa p981
Robert W. Gess, Michael I. Coates and Bruce S. Rubidge
doi:10.1038/nature05150
First paragraph | Full Text | PDF (892K) | Supplementary information
See also: Editor's summary | News and Views by Janvier
--------------------------------------------------------------------------------
Regulatory constraints in the evolution of the tetrapod limb anterior–posterior polarity p985
Basile Tarchini, Denis Duboule and Marie Kmita
doi:10.1038/nature05247
First paragraph | Full Text | PDF (558K)
See also: Editor's summary
--------------------------------------------------------------------------------
Effects of biodiversity on the functioning of trophic groups and ecosystems p989
Bradley J. Cardinale, Diane S. Srivastava, J. Emmett Duffy, Justin P. Wright, Amy L. Downing, Mahesh Sankaran and Claire Jouseau
doi:10.1038/nature05202
First paragraph | Full Text | PDF (470K) | Supplementary information
See also: Editor's summary
--------------------------------------------------------------------------------
Corneal avascularity is due to soluble VEGF receptor-1 p993
Balamurali K. Ambati, Miho Nozaki, Nirbhai Singh, Atsunobu Takeda, Pooja D. Jani, Tushar Suthar, Romulo J. C. Albuquerque, Elizabeth Richter, Eiji Sakurai, Michael T. Newcomb, Mark E. Kleinman, Ruth B. Caldwell, Qing Lin, Yuichiro Ogura, Angela Orecchia, Don A. Samuelson, Dalen W. Agnew, Judy St. Leger, W. Richard Green, Parameshwar J. Mahasreshti, David T. Curiel, Donna Kwan, Helene Marsh, Sakae Ikeda, Lucy J. Leiper, J. Martin Collinson, Sasha Bogdanovich, Tejvir S. Khurana, Masabumi Shibuya, Megan E. Baldwin, Napoleone Ferrara, Hans-Peter Gerber, Sandro De Falco, Jassir Witta, Judit Z. Baffi, Brian J. Raisler and Jayakrishna Ambati
doi:10.1038/nature05249
First paragraph | Full Text | PDF (600K) | Supplementary information
See also: Editor's summary | News and Views by Marte
--------------------------------------------------------------------------------
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages p998
Kohki Kawane, Mayumi Ohtani, Keiko Miwa, Takuji Kizawa, Yoshiyuki Kanbara, Yoshichika Yoshioka, Hideki Yoshikawa and Shigekazu Nagata
doi:10.1038/nature05245
First paragraph | Full Text | PDF (910K) | Supplementary information
See also: Editor's summary
--------------------------------------------------------------------------------
Amplification of histone genes by circular chromosome formation in Saccharomyces cerevisiae p1003
Diana E. Libuda and Fred Winston
doi:10.1038/nature05205
First paragraph | Full Text | PDF (473K) | Supplementary information
See also: Editor's summary
--------------------------------------------------------------------------------
Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation p1008
Yijun Qi, Xingyue He, Xiu-Jie Wang, Oleksiy Kohany, Jerzy Jurka and Gregory J. Hannon
doi:10.1038/nature05198
First paragraph | Full Text | PDF (474K) | Supplementary information
--------------------------------------------------------------------------------
Corrigendum: The DNA sequence and biological annotation of human chromosome 1 p1013
S. G. Gregory, K. F. Barlow, K. E. McLay, R. Kaul, D. Swarbreck, A. Dunham, C. E. Scott, K. L. Howe, K. Woodfine, C. C. A. Spencer, M. C. Jones, C. Gillson, S. Searle, Y. Zhou, F. Kokocinski, L. McDonald, R. Evans, K. Phillips, A. Atkinson, R. Cooper, C. Jones, R. E. Hall, T. D. Andrews, C. Lloyd, R. Ainscough, J. P. Almeida, K. D. Ambrose, F. Anderson, R. W. Andrew, R. I. S. Ashwell, K. Aubin, A. K. Babbage, C. L. Bagguley, J. Bailey, R. Banerjee, H. Beasley, G. Bethel, C. P. Bird, S. Bray-Allen, J. Y. Brown, A. J. Brown, S. P. Bryant, D. Buckley, D. C. Burford, W. D. H. Burrill, J. Burton, J. Bye, C. Carder, J. C. Chapman, S. Y. Clark, G. Clarke, C. Clee, S. M. Clegg, V. Cobley, R. E. Collier, N. Corby, G. J. Coville, J. Davies, R. Deadman, P. Dhami, O. Dovey, M. Dunn, M. Earthrowl, A. G. Ellington, H. Errington, L. M. Faulkner, A. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, L. Gay, M. R. J. Ghori, R. Gibson, L. M. Gilby, W. Gillett, R. J. Glithero, D. V. Grafham, S. M. Gribble, C. Griffiths, S. Griffiths-Jones, R. Grocock, S. Hammond, E. S. I. Harrison, E. Hart, E. Haugen, P. D. Heath, S. Holmes, K. Holt, P. J. Howden, A. R. Hunt, S. E. Hunt, G. Hunter, J. Isherwood, R. James, C. Johnson, D. Johnson, A. Joy, M. Kay, J. K. Kershaw, M. Kibukawa, A. M. Kimberley, A. King, A. J. Knights, H. Lad, G. Laird, C. F. Langford, S. Lawlor, D. A. Leongamornlert, D. M. Lloyd, J. Loveland, J. Lovell, M. J. Lush, R. Lyne, S. Martin, M. Mashreghi-Mohammadi, L. Matthews, N. S. W. Matthews, S. McLaren, S. Milne, S. Mistry, M. J. F. M. oore, T. Nickerson, C. N. O'Dell, K. Oliver, A. Palmeiri, S. A. Palmer, R. D. Pandian, A. Parker, D. Patel, A. V. Pearce, A. I. Peck, S. Pelan, K. Phelps, B. J. Phillimore, R. Plumb, K. M. Porter, E. Prigmore, J. Rajan, C. Raymond, G. Rouse, C. Saenphimmachak, H. K. Sehra, E. Sheridan, R. Shownkeen, S. Sims, C. D. Skuce, M. Smith, C. Steward, S. Subramanian, N. Sycamore, A. Tracey, A. Tromans, Z. Van Helmond, M. Wall J. M. Wallis, S. White, S. L. Whitehead, J. E. Wilkinson, D. L. Willey, H. Williams, L. Wilming, P. W. Wray, Z. Wu, A. Coulson, M. Vaudin, J. E. Sulston, R. Durbin, T. Hubbard, R. Wooster, I. Dunham, N. P. Carter, G. McVean, M. T. Ross, J. Harrow, M. V. Olson, S. Beck, J. Rogers and D. R. Bentley
doi:10.1038/nature05152
Full Text | PDF (56K)
--------------------------------------------------------------------------------
Retraction: Origin of the obliquities of the giant planets in mutual interactions in the early Solar System p1013
Adrián Brunini
doi:10.1038/nature05298
Full Text | PDF (56K)
--------------------------------------------------------------------------------
Corrigendum: Complete photo-fragmentation of the deuterium molecule p1014
T. Weber, A. O. Czasch, O. Jagutzki, A. K. Müller, V. Mergel, A. Kheifets, E. Rotenberg, G. Meigs, M. H. Prior, S. Daveau, A. Landers, C. L. Cocke, T. Osipov, R. Díez Muiño, H. Schmidt-Böcking and R. Dörner
doi:10.1038/nature05296
First paragraph | Full Text | PDF (135K)
--------------------------------------------------------------------------------
Top of pageTechnology Features
Something to see p1017
Light microscopy is undergoing a renaissance, with a huge range of tools and techniques for gathering biological data with unprecedented speed and resolution. Michael Eisenstein takes a closer look.
Michael Eisenstein
doi:10.1038/4431017a
Full Text | PDF (430K)
--------------------------------------------------------------------------------
Achieving clarity p1017
doi:10.1038/4431017b
Full Text | PDF (147K)
--------------------------------------------------------------------------------
Thinking big, seeing small p1019
doi:10.1038/4431019a
Full Text | PDF (255K)
--------------------------------------------------------------------------------
Tower of Babel p1021
doi:10.1038/4431021a
Full Text | PDF (163K)
--------------------------------------------------------------------------------
Top of pageNaturejobs
Prospect
Prospects p1025
UK academic salary analysis offers mixed news.
Paul Smaglik
doi:10.1038/nj7114-1025a
Full Text | PDF (176K)
--------------------------------------------------------------------------------
Region
Northern exposure p1026
An alliance of universities in the north of England hopes to transform Britain's former industrial heartland into a centre of scientific excellence. Paul Smaglik reports.
Paul Smaglik
doi:10.1038/nj7114-1026a
Full Text | PDF (652K)
--------------------------------------------------------------------------------
Career Views
Carl Pilcher, director, NASA Astrobiology Institute, Moffett Field, California p1028
Virginia Gewin
doi:10.1038/nj7114-1028a
Full Text | PDF (98K)
--------------------------------------------------------------------------------
Made-to-measure postdocs p1028
Mandë Holford
doi:10.1038/nj7114-1028b
Full Text | PDF (98K)
--------------------------------------------------------------------------------
How studies can save a life p1028
Milan de Vries
doi:10.1038/nj7114-1028c
Full Text | PDF (98K)
--------------------------------------------------------------------------------
Spotlight
Spotlight: N8 Group
doi:10.1038/nj0129
Full Text | PDF (3,518K)
--------------------------------------------------------------------------------
Top of pageFutures
Take over p1030
A real identity crisis.
Jon Courtenay Grimwood
doi:10.1038/4431030a
Full Text | PDF (156K)
