Science 1 December 2006: 1437-1439.
Published online 2 November 2006 [DOI: 10.1126/science.1134231] (in Science Express Reports)
Circular dichroism spectra at high resolution reveal that weak aggregate signals arise because the effects of distinct conformations in a chiral ensemble cancel each other.
Abstract »| Full Text »| PDF »|
Organic Globules in the Tagish Lake Meteorite: Remnants of the Protosolar Disk
Keiko Nakamura-Messenger, Scott Messenger, Lindsay P. Keller, Simon J. Clemett, and Michael E. Zolensky
Science 1 December 2006: 1439-1442.
Carbon-rich nanospheres in a primitive meteorite are relatively enriched in the heavy nitrogen isotopes and deuterium, suggesting that these grains have a pre-solar origin.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Increasing Trend of Extreme Rain Events Over India in a Warming Environment
B. N. Goswami, V. Venugopal, D. Sengupta, M. S. Madhusoodanan, and Prince K. Xavier
Science 1 December 2006: 1442-1445.
The frequency and intensity of heavy rainfall events during monsoon storms in Central India have increased during the past 50 years as the climate there has warmed.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Male Fertility and Sex Ratio at Birth in Red Deer
Montserrat Gomendio, Aurelio F. Malo, Ana J. Soler, Maria R. Fernández-Santos, Milagros C. Esteso, Andrés J. García, Eduardo R. S. Roldan, and Julian Garde
Science 1 December 2006: 1445-1447.
Like females, males can affect offspring sex ratio; more-fertile male red deer sire more sons and less-fertile males sire more daughters.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
WNT and DKK Determine Hair Follicle Spacing Through a Reaction-Diffusion Mechanism
Stefanie Sick, Stefan Reinker, Jens Timmer, and Thomas Schlake
Science 1 December 2006: 1447-1450.
Published online 2 November 2006 [DOI: 10.1126/science.1130088] (in Science Express Reports)
Modeling and experimental tests explain how a growth factor and its inhibitor determine the density and pattern of hair follicles in the developing mouse.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Structural Basis for Ribosome Recruitment and Manipulation by a Viral IRES RNA
Jennifer S. Pfingsten, David A. Costantino, and Jeffrey S. Kieft
Science 1 December 2006: 1450-1454.
Published online 23 November 2006 [DOI: 10.1126/science.1133281] (in Science Express Reports)
The structure of a viral RNA containing an internal ribosomal entry site suggests how translation can begin in the middle of a messenger RNA.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Rapid Chemically Induced Changes of PtdIns(4,5)P2 Gate KCNQ Ion Channels
Byung-Chang Suh, Takanari Inoue, Tobias Meyer, and Bertil Hille
Science 1 December 2006: 1454-1457.
Published online 21 September 2006 [DOI: 10.1126/science.1131163] (in Science Express Reports)
Neurotransmitters close a potassium channel by changing the lipid content of the surrounding plasma membrane.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane
Won Do Heo, Takanari Inoue, Wei Sun Park, Man Lyang Kim, Byung Ouk Park, Thomas J. Wandless, and Tobias Meyer
Science 1 December 2006: 1458-1461.
Published online 9 November 2006 [DOI: 10.1126/science.1134389] (in Science Express Reports)
Two phospholipid signaling molecules are also essential to anchor proteins that have clusters of basic amino acids to the cell membrane.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
Richard H. Duerr, Kent D. Taylor, Steven R. Brant, John D. Rioux, Mark S. Silverberg, Mark J. Daly, A. Hillary Steinhart, Clara Abraham, Miguel Regueiro, Anne Griffiths, Themistocles Dassopoulos, Alain Bitton, Huiying Yang, Stephan Targan, Lisa Wu Datta, Emily O. Kistner, L. Philip Schumm, Annette T. Lee, Peter K. Gregersen, M. Michael Barmada, Jerome I. Rotter, Dan L. Nicolae, and Judy H. Cho
Science 1 December 2006: 1461-1463.
Published online 26 October 2006 [DOI: 10.1126/science.1135245] (in Science Express Reports)
People with a rare sequence variant of the gene encoding the receptor for an immunological cytokine have a reduced risk of inflammatory bowel disease.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria
Elizabeth A. Ottesen, Jong Wook Hong, Stephen R. Quake, and Jared R. Leadbetter
Science 1 December 2006: 1464-1467.
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