Science 5 January 2007: 87-91. The covariance of atmospheric CO2 levels, surface temperatures, and global ice volume indicates that greenhouse gases controlled climate about 300 million years ago. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Late-Neoproterozoic Deep-Ocean Oxygenation and the Rise of Animal Life Don E. Canfield, Simon W. Poulton, and Guy M. Narbonne Science 5 January 2007: 92-95. Published online 7 December 2006 [DOI: 10.1126/science.1135013] (in Science Express Reports) A record based on iron species in minerals implies that the deep ocean only became oxygenated after the last major Precambrian glaciation, just before the rise of metazoans. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Climate Change Affects Marine Fishes Through the Oxygen Limitation of Thermal Tolerance Hans O. Pörtner and Rainer Knust Science 5 January 2007: 95-97. The eelpout needs more oxygen at higher temperatures, but because the warmed water in the North Sea carries less oxygen, the fish are becoming smaller and scarcer there. Abstract »| Full Text »| PDF »| Supporting Online Material »|
A Hexanucleotide Element Directs MicroRNA Nuclear Import Hun-Way Hwang, Erik A. Wentzel, and Joshua T. Mendell Science 5 January 2007: 97-100. A six-nucleotide sequence near one end of a small noncoding RNA determines its location in the cell nucleus. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Left-Right Dynein Motor Implicated in Selective Chromatid Segregation in Mouse Cells Athanasios Armakolas and Amar J. S. Klar Science 5 January 2007: 100-101. A gene known to control left-right asymmetry during development also regulates whether a mouse chromosome segregates randomly during cell division. Abstract »| Full Text »| PDF »| Supporting Online Material »|
A Cytokinin Perception Mutant Colonized by Rhizobium in the Absence of Nodule Organogenesis Jeremy D. Murray, Bogumil J. Karas, Shusei Sato, Satoshi Tabata, Lisa Amyot, and Krzysztof Szczyglowski Science 5 January 2007: 101-104. Published online 16 November 2006 [DOI: 10.1126/science.1132514] (in Science Express Reports) In the legume Lotus, symbiotic, nitrogen-fixing bacteria induce formation of the root nodules in which they reside by eliciting a growth response from the plant itself. Abstract »| Full Text »| PDF »| Supporting Online Material »| A Gain-of-Function Mutation in a Cytokinin Receptor Triggers Spontaneous Root Nodule Organogenesis Leïla Tirichine, Niels Sandal, Lene H. Madsen, Simona Radutoiu, Anita S. Albrektsen, Shusei Sato, Erika Asamizu, Satoshi Tabata, and Jens Stougaard Science 5 January 2007: 104-107. Published online 16 November 2006 [DOI: 10.1126/science.1132397] (in Science Express Reports) In the legume Lotus, symbiotic, nitrogen-fixing bacteria induce formation of the root nodules in which they reside by eliciting a growth response from the plant itself. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Differential Antigen Processing by Dendritic Cell Subsets in Vivo Diana Dudziak, Alice O. Kamphorst, Gordon F. Heidkamp, Veit R. Buchholz, Christine Trumpfheller, Sayuri Yamazaki, Cheolho Cheong, Kang Liu, Han-Woong Lee, Chae Gyu Park, Ralph M. Steinman, and Michel C. Nussenzweig Science 5 January 2007: 107-111. Two different types of dendritic cells in the immune system present antigen in different ways to elicit distinct immune responses. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Differential Transmission of Actin Motion Within Focal Adhesions Ke Hu, Lin Ji, Kathryn T. Applegate, Gaudenz Danuser, and Clare M. Waterman-Storer Science 5 January 2007: 111-115. Adhesions on a cell membrane act as molecular clutches to transmit forces from the actin cytoskeleton within a cell to the extracellular substrate, directing cell movement. Abstract »| Full Text »| PDF »| Supporting Online Material »|
Live-Cell Imaging of Enzyme-Substrate Interaction Reveals Spatial Regulation of PTP1B Ivan A. Yudushkin, Andreas Schleifenbaum, Ali Kinkhabwala, Benjamin G. Neel, Carsten Schultz, and Philippe I. H. Bastiaens Science 5 January 2007: 115-119. Fluorescence imaging microscopy can distinguish enzyme molecules within a single cell that are actively involved in signaling versus ones that are being deactivated. Abstract »| Full Text »| PDF »| Supporting Online Material »|
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