Bioinformatics and the Cell: Modern Approaches in Genomics, Proteomics and Trans

Bioinformatics and the Cell: Modern Approaches in Genomics, Proteomics and Transcriptomics

* Publisher: Springer
* Number Of Pages: 350
* Publication Date: 2007-06
* Sales Rank:
* ISBN / ASIN: 0387713360
* EAN: 9780387713366
* Binding: Hardcover
* Manufacturer: Springer
* Studio: Springer
* Average Rating:
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Book Description:
The many books that have been written on bioinformatics tend to fall on two extremes: books that feature computational details with a great deal of mathematics, for computational scientists and mathematicians, or books that treat bioinformatics mostly as a giant black box, for biologists. Previous books written on bioinformatics often have limited contribution to creating interdisciplinary scientists needed in modern biological and biomedical sciences.

This book aims to render both mathematical equations and biology to numbers, to help truly interdisciplinary scientists. Although the book covers bioinformatics methods at a level more advanced than most other bioinformatics books, the extensive numerical illustration of these methods should make it accessible to most senior undergraduate students and graduate students majoring in science and software engineering. Nearly all algorithms in the book are implemented in a free and user-friendly computer program (DAMBE).

Written for:
Researchers, graduate students, post docs in biology working in bioinformatics, genomics, proteomics

Table of contents
BLAST and FASTA.- Sequence Alignment.- Contig Assembly.- DNA Replication and Viral Evolution.- Gene and Motif Prediction.- Hidden Markov Models.- Gibbs Sampler.- Bioinformatics and Vertebrate Mitochondria.- Characterizing Translation Efficiency.- Protein Isoelectric Point.- Bioinformatics and Two-Dimensional Protein Separation.- Self-Organizing Map and Other Clustering Algorithms.- Molecular Phylogenetics.- Fundamentals of Proteomics.

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