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The Genetics of Osteoporosis and Metabolic Bone Disease

Publisher: Humana Press Number Of Pages: 462 Publication Date: 2000-06-15 Sales Rank: 2466723 ISBN / ASIN: 0896037029 EAN: 9780896037021 Binding: Hardcover Manufacturer: Humana Press Studio: Humana Press
Michael J. Econs and a distinguished team of internationally renowned experts summarize and review the latest understanding of the genetics of osteoporosis and metabolic bone disease. Topics range from an examination of the genetic contributions to osteoporosis and the many factors that must be considered when searching for genes that predispose to osteoporosis, to recent advances in the clinical and molecular biological aspects of inherited metabolic disorders. The diseases covered are both single-gene (Mendelian) traits-such as X-linked hypophosphatemic rickets-and such complex disorders as osteoporosis and Paget's disease. The book includes a discussion of current methodology for finding genes that predispose to metabolic bone diseases. Authoritative and state-of-the-art, The Genetics of Osteoporosis and Metabolic Bone Disease offers today's endocrinologists, rheumatologists, and geneticists a gold-standard compendium of current knowledge and thinking about the genetic disorders of bone and mineral metabolism, and a sound basis for powerful new genetic therapies.
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